Reproductive and Developmental Toxicity

Reproductive and developmental toxicology deals with the identification of the effects of pharmaceuticals and chemicals on the mammalian reproduction at all developmental stages.

Toxi-Coop have performed a large number of reproductive toxicity studies for pharmaceuticals, agricultural and industrial chemicals in accordance with the OECD, ICH, FDA, EMEA and OPPTS guidelines.

Main Study Options

  • • Fertility and reproduction studies (one, two generation studies, combined repeat dose toxicity with repro screening test)
  • • Prenatal developmental toxicity studies (assessment of skeleton and soft tissues)
  • • Perinatal and postnatal studies (neurodevelopmental, immuno-developmental studies)
  • • Combined general toxicity-reproductive toxicity studies

Study Types

  • • Reproduction / developmental screening study OECD 421
  • • Prenatal developmental toxicity study OECD 414
  • • One-generation reproduction toxicity study OECD 421
  • • Two generations reproduction toxicity study OECD 416